abstract：PURPOSE:To report normative data on visual acuity (VA) for near and distance, refraction, ocular alignment, ocular motility and stereo acuity in a cohort of children aged 4.5-7 years. METHODS:A total of 950 children with normal development from the municipality of Roskilde, Denmark, were invited to participate in an o...

journal_title：Acta ophthalmologica

authors： Sandfeld L,Weihrauch H,Tubaek G,Mortzos P

更新日期：2018-06-01 00:00:00

abstract：:There is still no agreement on total plasma homocysteine (tHcy) role in age-related macular degeneration (AMD), the leading cause of new blindness in industrialized countries. We performed a systematic review and meta-analysis of the published data on the correlation between tHcy and AMD. MEDLINE/PubMed and ISI Web of...

journal_title：Acta ophthalmologica

authors： Pinna A,Zaccheddu F,Boscia F,Carru C,Solinas G

更新日期：2018-05-01 00:00:00

abstract：PURPOSE:To investigate the feasibility, effectiveness and acceptability of using prosthetic occluding contact lenses (OCLs) to treat moderate amblyopia in adults and of the role of the multifocal visual evoked potential (mfVEP) as a predictor of postamblyopic therapy. METHODS:A comparative, prospective, interventional...

journal_title：Acta ophthalmologica

authors： Garcia-Romo E,Perez-Rico C,Roldán-Díaz I,Arévalo-Serrano J,Blanco R

更新日期：2018-05-01 00:00:00

abstract：PURPOSE:To evaluate the impact of dynamic exercise on retinal vessel oxygen saturation in healthy individuals. METHODS:Twenty-six healthy participants underwent moderate dynamic exercise (modified Master's two-step exercise). In all subjects, intraocular pressures (IOP), systolic and diastolic blood pressures (SBP and...

journal_title：Acta ophthalmologica

authors： Heitmar R,Vekria P,Cubbidge RP

更新日期：2018-05-01 00:00:00

abstract：PURPOSE:To determine (i) whether, compared to controls, visual complaints of glaucoma patients are more pronounced under extreme luminance conditions than in the optimal luminance condition and (ii) whether complaints belonging to different extreme luminance conditions are associated. METHODS:We developed a luminance-...

journal_title：Acta ophthalmologica

authors： Bierings RAJM,van Sonderen FLP,Jansonius NM

更新日期：2018-05-01 00:00:00

abstract：PURPOSE:To compare the postoperative anatomic success rates and the frequency of complications between prone or supine postoperative positioning after transconjunctival sutureless vitrectomy (TSV) for rhegmatogenous retinal detachment (RRD). METHODS:All patients underwent primary 27-gauge TSV for the treatment of prim...

journal_title：Acta ophthalmologica

authors： Otsuka K,Imai H,Miki A,Nakamura M

更新日期：2018-03-01 00:00:00

abstract：PURPOSE:Chronic inflammation is involved in retinitis pigmentosa (RP). We demonstrated previously that intraocular inflammatory levels, as measured by slit-lamp ophthalmoscopy or laser flare photometry, are inversely correlated with central visual function in patients with RP. Here, we investigated the relationship bet...

journal_title：Acta ophthalmologica

authors： Murakami Y,Ikeda Y,Nakatake S,Fujiwara K,Tachibana T,Yoshida N,Notomi S,Hisatomi T,Yoshida S,Ishibashi T,Sonoda KH

更新日期：2018-03-01 00:00:00

abstract：PURPOSE:We aimed to assess the macular anatomy using spectral domain optical coherence tomography (SD-OCT), in children born preterm who had laser-treated retinopathy of prematurity (ROP), and to investigate the relationship between structural changes in macula and visual function. METHODS:Thirty-seven 3-8 years old c...

journal_title：Acta ophthalmologica

authors： Stoica F,Chirita-Emandi A,Andreescu N,Stanciu A,Zimbru CG,Puiu M

更新日期：2018-03-01 00:00:00

abstract：PURPOSE:To determine associations between physical activity (PA) and myopia in Danish school children and investigate the prevalence of myopia. METHODS:This is a prospective study with longitudinal data on PA in a Danish child cohort. Physical activity (PA) was measured objectively by repeated ActiGraph accelerometer ...

journal_title：Acta ophthalmologica

authors： Lundberg K,Suhr Thykjaer A,Søgaard Hansen R,Vestergaard AH,Jacobsen N,Goldschmidt E,Lima RA,Peto T,Wedderkopp N,Grauslund J

更新日期：2018-03-01 00:00:00

abstract：PURPOSE:To study the genetic aetiology of retinal dystrophies (RD) in Finnish patients. METHODS:A targeted next-generation sequencing (NGS) panel of 105 retinal dystrophy genes was used in a cohort of 55 RD patients. RESULTS:The overall diagnostic yield was 60% demonstrating the power of this approach. Interestingly,...

journal_title：Acta ophthalmologica

authors： Avela K,Sankila EM,Seitsonen S,Kuuluvainen L,Barton S,Gillies S,Aittomäki K

更新日期：2018-03-01 00:00:00

abstract：PURPOSE:As some surgical procedures have been shown to increase postoperative flare values and thus contribute to blood-ocular barrier breakdown, retinal reattachment surgery might influence the risk of developing proliferative vitreoretinopathy (PVR). Therefore, we investigated whether postoperative aqueous flare valu...

journal_title：Acta ophthalmologica

authors： Mulder VC,van Dijk EHC,van Meurs IA,La Heij EC,van Meurs JC

更新日期：2018-03-01 00:00:00

abstract：PURPOSE:To examine the movement of air injected in the cornea in simulated deep anterior lamellar keratoplasty (DALK), from the needle tip to the formation of different types of big bubbles (BB) and to ascertain how air travels through the stroma and pre-Descemet's layer [Dua's layer (PDL)] to create a type-1 (air betw...

journal_title：Acta ophthalmologica

authors： Dua HS,Faraj LA,Kenawy MB,AlTaan S,Elalfy MS,Katamish T,Said DG

更新日期：2018-02-01 00:00:00

abstract：PURPOSE:Tissue inhibitors of metalloproteinases (TIMPs) block the catalysis by matrix metalloproteinases (MMPs) and have additional biologic activities, including regulation of cell growth and differentiation, apoptosis, angiogenesis and oncogenesis. We investigated the expression levels of all the four human TIMPs and...

journal_title：Acta ophthalmologica

authors： Abu El-Asrar AM,Ahmad A,Bittoun E,Siddiquei MM,Mohammad G,Mousa A,De Hertogh G,Opdenakker G

更新日期：2018-02-01 00:00:00

abstract：PURPOSE:The purpose of this study was to investigate the safety and efficacy of phacocanaloplasty with suprachoroidal drainage (PCscD) and to compare its intraocular pressure (IOP)-lowering and drug-sparing effect to canaloplasty with suprachoroidal drainage (CscD). METHODS:The study retrospective interventional study...

journal_title：Acta ophthalmologica

authors： Seuthe AM,Januschowski K,Mariacher S,Ebner M,Opitz N,Szurman P,Boden K

更新日期：2018-02-01 00:00:00

abstract：AIM:To report basic epidemiological data concerning surgically treated childhood cataract in Sweden and Denmark. METHODS:Data were derived from the Paediatric Cataract Register (PECARE), a binational, web-based surgical register representing Sweden and Denmark. All children operated before 8 years of age between 1 Jan...

journal_title：Acta ophthalmologica

authors： Magnusson G,Haargaard B,Basit S,Lundvall A,Nyström A,Rosensvärd A,Tornqvist K

更新日期：2018-02-01 00:00:00

abstract：PURPOSE:To compare the outcomes of microcatheter-assisted circumferential trabeculotomy to standard rigid probe trabeculotomy in childhood glaucomas. METHODS:Eyes of children requiring trabeculotomy for primary congenital or secondary paediatric glaucoma were randomized to undergo either trabeculotomy using the Glauco...

journal_title：Acta ophthalmologica

authors： El Sayed Y,Gawdat G

更新日期：2017-12-01 00:00:00

abstract：PURPOSE:To evaluate the regenerating potential and the mechanisms through which the autologous serum derived from plasma rich in growth factors (s-PRGF) favours corneal wound healing in vitro and in vivo. METHODS:We compared the effect of various concentrations of s-PRGF versus fetal bovine serum (FBS) and control tre...

journal_title：Acta ophthalmologica

authors： Etxebarria J,Sanz-Lázaro S,Hernáez-Moya R,Freire V,Durán JA,Morales MC,Andollo N

更新日期：2017-12-01 00:00:00

abstract：PURPOSE:To investigate long-term visual results of treatment with anti-vascular endothelial growth factor (VEGF) agents for neovascular age-related macular degeneration (nAMD) following a treat-and-extend regimen. METHODS:Retrospective review of 155 patients who initiated treatment with bevacizumab for nAMD in one eye...

journal_title：Acta ophthalmologica

authors： Berg K,Roald AB,Navaratnam J,Bragadóttir R

更新日期：2017-12-01 00:00:00

abstract：:Data on the association between hypothyroidism and glaucoma are conflicting. We sought to shed light on this by conducting a critical review and meta-analyses. The meta-analyses were conducted in adherence with the widely accepted MOOSE guidelines. Using the Medical Subject Heading (MeSH) terms: hypothyroidism, myxoed...

journal_title：Acta ophthalmologica

authors： Thvilum M,Brandt F,Brix TH,Hegedüs L

更新日期：2017-12-01 00:00:00

abstract：PURPOSE:Current fundus imaging in newborn babies requires mydriatics, eye specula and corneal contact. We propose that a scanning laser ophthalmoscope (SLO) allows ultra wide-field imaging with reduced stress for the child. METHODS:This prospective observational single centre study was conducted in Landspítali, Univer...

journal_title：Acta ophthalmologica

authors： Magnusdottir V,Vehmeijer WB,Eliasdottir TS,Hardarson SH,Schalij-Delfos NE,Stefánsson E

更新日期：2017-12-01 00:00:00

abstract：PURPOSE:To describe the retinal structure of a group of patients affected by methylmalonic aciduria with homocystinuria cblC type, caused by mutations in the MMACHC gene, using spectral domain optical coherence tomography (SD-OCT). METHODS:Young patients (n = 11, age 0-74 months) with cblC disease, detected by newborn...

journal_title：Acta ophthalmologica

authors： Bacci GM,Donati MA,Pasquini E,Munier F,Cavicchi C,Morrone A,Sodi A,Murro V,Garcia Segarra N,Defilippi C,Bussolin L,Caputo R

更新日期：2017-12-01 00:00:00

abstract：PURPOSE:To investigate the reproducibility of Bruch's membrane opening minimum rim width (BMO-MRW) and retinal nerve fibre layer thickness (RNFLT) measurements using spectral domain optical coherence tomography (SD-OCT). Additionally, to investigate the reproducibility of BMO area measurements and fovea to BMO centre (...

journal_title：Acta ophthalmologica

authors： Reis ASC,Zangalli CES,Abe RY,Silva AL,Vianna JR,Vasconcellos JPC,Costa VP

更新日期：2017-11-01 00:00:00

abstract：PURPOSE:To identify and determine differences in lipid profile of aqueous humour (AH) in patients with Fuchs endothelial corneal dystrophy (FECD). METHODS:Lipidomic profile of eight AH samples of FECD patients and 10 control samples was analysed. Patients with previous history of anterior segment surgery, anterior seg...

journal_title：Acta ophthalmologica

authors： Cabrerizo J,Urcola JA,Vecino E,Melles G

更新日期：2017-11-01 00:00:00

abstract：PURPOSE:To compare subconjunctival scarring after vitrectomy in rabbit eyes using different gauge systems by analysing anterior segment optical coherence tomography (AS-OCT) images and histological sections. METHODS:Vitrectomy using 20-, 23-, 25- and 27-gauge systems was performed for rabbits. Anterior segment optical...

journal_title：Acta ophthalmologica

authors： Gozawa M,Takamura Y,Miyake S,Iwasaki K,Arimura S,Takihara Y,Inatani M

更新日期：2017-11-01 00:00:00

abstract：PURPOSE:This study sought to determine whether isolated third, fourth and sixth cranial nerve palsies (NPs) are associated with increased short- and long-term risk of a subsequent stroke. METHODS:This was a nationwide retrospective propensity score-matched cohort study. A cohort of patients with NP (n = 466) and a ran...

journal_title：Acta ophthalmologica

authors： Rim TH,Han J,Choi YS,Lee T,Kim SS

更新日期：2017-11-01 00:00:00

abstract：PURPOSE:To assess thickness and associations of the peripapillary choroidal layers. METHODS:The population-based Beijing Eye Study included 3468 participants with an age of 50+ years. Using spectral-domain optical coherence tomography, we measured the large vessel layer (LVL) and small-to-medium vessel layer (SMVL) of...

journal_title：Acta ophthalmologica

authors： Xu J,Wang YX,Jiang R,Wei WB,Xu L,Jonas JB

更新日期：2017-09-01 00:00:00

abstract：PURPOSE:To examine the potential of intravitreally implanted human bone marrow-derived mesenchymal stem cells (BMSCs) to affect vascular repair and the blood-retina barrier in mice and rats with oxygen-induced retinopathy, diabetic retinopathy or retinal ischaemia-reperfusion damage. METHODS:Three study groups (oxygen...

journal_title：Acta ophthalmologica

authors： Wang JD,An Y,Zhang JS,Wan XH,Jonas JB,Xu L,Zhang W

更新日期：2017-09-01 00:00:00

abstract：PURPOSE:To assess the retinal vessel blood oxygen saturation preoperatively and postoperatively in patients with different grades of cataracts. METHODS:This study included 40 eyes from 40 patients with senile cataracts ranging from grade 1 to 3. All 40 eyes received standard phacoemulsification and intraocular lens im...

journal_title：Acta ophthalmologica

authors： Chen H,Lin H,Chen W,Zhang B,Xiang W,Gao Q,Chen W,Liu Y

更新日期：2017-09-01 00:00:00

abstract：PURPOSE:To assess the surgical and functional outcome of internal direct cyclopexy as therapy of complicated traumatic cyclodialysis. METHODS:The single-centre interventional case-series study included eyes with traumatic cyclodialysis who had consecutively been treated. Internal cyclopexy was performed using double-a...

journal_title：Acta ophthalmologica

authors： Wang C,Peng XY,You QS,Liu Y,Pang XQ,Zheng PF,Jonas JB

更新日期：2017-09-01 00:00:00

abstract：PURPOSE:To assess the presence of outer and inner retinal folds (RFs) and drop-out of the ellipsoid zone (EZ) occurring after surgical repair of macula-off rhegmatogenous retinal detachment (RRD) with different postoperative posture and preoperative use of adjuvant perfluorocarbon liquid (PFCO). METHODS:In this prospe...

journal_title：Acta ophthalmologica

authors： Peiretti E,Nasini F,Buschini E,Caminiti G,Lesnik Oberstein SY,Willig A,Bijl HM,Mura M

更新日期：2017-08-01 00:00:00

abstract：PURPOSE:To study anisometropia of spherical equivalent and astigmatism from the onset of myopia at school age to adulthood. METHODS:A total of 240 myopic schoolchildren (mean age 10.9 years), with no previous spectacles, were recruited during 1983-1984 to a randomized 3-year clinical trial of bifocal treatment of myop...

journal_title：Acta ophthalmologica

authors： Pärssinen O,Kauppinen M

更新日期：2017-08-01 00:00:00

abstract：PURPOSE:To determine the molecular genetic cause in previously unreported probands with optic atrophy from the United Kingdom, Czech Republic and Canada. METHODS:OPA1 coding regions and flanking intronic sequences were screened by direct sequencing in 82 probands referred with a diagnosis of bilateral optic atrophy. D...

journal_title：Acta ophthalmologica

authors： Liskova P,Tesarova M,Dudakova L,Svecova S,Kolarova H,Honzik T,Seto S,Votruba M

更新日期：2017-06-01 00:00:00

abstract：PURPOSE:To analyse pupil responses to specific chromatic stimuli in patients with advanced retinitis pigmentosa (RP) to ascertain whether chromatic pupillography can be used as an objective marker for residual retinal function. To examine correlations between parameters of the pupil response and the perception threshol...

journal_title：Acta ophthalmologica

authors： Kelbsch C,Maeda F,Lisowska J,Lisowski L,Strasser T,Stingl K,Wilhelm B,Wilhelm H,Peters T

更新日期：2017-06-01 00:00:00

abstract：PURPOSE:To evaluate a pro re nata administration of Ozurdex® implant versus a single administration for treating diabetic macular oedema (DME). METHODS:This exploratory study is designed as a comparative, multicentre, randomized study with a follow-up of 6 months. Patients with DME were assigned to treatment at baseli...

journal_title：Acta ophthalmologica

authors： Sarao V,Veritti D,Furino C,Giancipoli E,Alessio G,Boscia F,Lanzetta P

更新日期：2017-06-01 00:00:00

abstract：PURPOSE:To evaluate the incidence of central hole-induced ring-shaped dysphotopsia after posterior chamber phakic implantable collamer lens (ICL) with central hole (hole ICL) implantation and to investigate the causes of central hole-induced dysphotopsia. METHODS:The clinical study enrolled 29 eyes of 15 consecutive m...

journal_title：Acta ophthalmologica

authors： Eom Y,Kim DW,Ryu D,Kim JH,Yang SK,Song JS,Kim SW,Kim HM

更新日期：2017-05-01 00:00:00

abstract：PURPOSE:To evaluate the impact of pseudoexfoliation syndrome on intraocular lens (IOL) dislocation after phacoemulsification cataract surgery and explore possible associations related to surgical technique. METHODS:We systematically searched the MEDLINE, Embase, Web of Science, Cochrane, and Lilacs databases and grey ...

journal_title：Acta ophthalmologica

authors： Vazquez-Ferreiro P,Carrera-Hueso FJ,Fikri-Benbrahim N,Barreiro-Rodriguez L,Diaz-Rey M,Ramón Barrios MA

更新日期：2017-05-01 00:00:00

abstract：PURPOSE:Clinical risk management aims to identify, analyse and avoid errors and risks systematically to improve patient's safety. Preoperative checklists to prevent mistakes have gained importance in the last few years. A so-called team timeout checklist was introduced in October 2011 at the Department of Ophthalmology...

journal_title：Acta ophthalmologica

authors： Weingessel B,Haas M,Vécsei C,Vécsei-Marlovits PV

更新日期：2017-03-01 00:00:00

abstract：PURPOSE:To report our experience in endoscopic dacryocystorhinostomy in treating nasolacrimal duct obstruction over a 14-year period. METHODS:Retrospective case series carried out over a 14-year period from 1999 to 2014. A total of 624 endoscopic dacryocystorhinostomy procedures were performed in 442 patients who were...

journal_title：Acta ophthalmologica

authors： Coumou AD,Genders SW,Smid TM,Saeed P

更新日期：2017-02-01 00:00:00

abstract：PURPOSE:Glaucoma filtration surgery (GFS) fails due to fibrosis. The α5β1-integrin plays a pivotal role in fibrosis, angiogenesis and inflammation. This is the first experiment evaluating the prevention of fibrosis after GFS by a specific small molecule α5β1-integrin inhibitor (CLT-28643). METHODS:Twenty-four rabbits ...

journal_title：Acta ophthalmologica

authors： Schultheiss M,Schnichels S,Konrad EM,Bartz-Schmidt KU,Zahn G,Caldirola P,Fsadni MG,Caram-Lelham N,Spitzer MS

更新日期：2017-02-01 00:00:00

abstract：PURPOSE:To assess the effects of multifocal soft contact lenses (MF SCLs) used for myopia control on visual acuity (VA) and subjective quality of vision. METHODS:Twenty-four young adult myopes had baseline high and low-contrast VAs and refractions measured and quality of vision assessed by the Quality of Vision (QoV) ...

journal_title：Acta ophthalmologica

authors： Kang P,McAlinden C,Wildsoet CF

更新日期：2017-02-01 00:00:00